1、Published by ECI Digital Archives, 2010 1 外文标题： DEM-CFD MODELLING OF A FLUIDIZED BED SPRAY GRANULATOR 外文作者： L Fries ， SH Sergiy Antonyuk ， S Palzer 文献出处 :International Conference on Fluidization-new Paradigm in Fluidization Engineering , 2011 , 66 (11) :2340 2355 英文 2657单词， 13788 字符，中文 3
2、698 汉字。 此文档是外文翻译成品，无需调整复杂的格式哦！下载之后直接可用，方便快捷！只需二十多元。 DEM-CFD MODELLING OF A FLUIDIZED BED SPRAY GRANULATOR Lennart Fries, Sergiy Antonyuk, Stefan Heinrich1 and Stefan Palzer 1 Institute of Solids Process Engineering and Particle Technology, Hamburg University of Technology Denickestrasse
3、15 21073 Hamburg, Germany T:+49-40-42878 2143; F:+49-40-42878-2678; E: lennart.friestuhh.de Nestl Research Center Vers-Chez-Les-Blanc, Department of Food Science and Technology Route du Jorat 57 1000 Lausanne 26, Switzerland ABSTRACT Coupled DEM-CFD simulations have been performed to study the hydro
4、dynamics of a Wurster granulator on the scale of individual particles. Based on extensive material tests, the collision behaviour of dry -Al2O3 particles is identified and incorporated into the model. The effect of process parameters like air flow rate and geometry details like the Wurster position
5、is studied. Based on a physical description of the material properties, an effective tool for design and scale-up of a Wurster granulator is obtained. INTRODUCTION Fluidized bed spray granulation plays an important role in the manufacturing of powder granules in the food and pharmaceutical ind
6、ustries as it allows producing dust-free and free-flowing particles. Liquid binder is sprayed into a bed of solids to achieve granule growth. Looking on the micro-scale, after the impact of droplets on granules or primary particles and wetting of the particles surface, drying of the binder layer and evaporation of the solvent initiates layer-wise binder deposition (coating). The Wurster is a common technique in the pharmaceutical industry used to coat tablets. A cylindrical draft tube is inserted vertically int
