1、中文 7400 字 出处： Huch M, Gehart H, Vanboxtel R, et al. Long-term culture of genome-stable bipotent stem cells from adult human liverJ. Cell, 2015, 160(1-2):299-312. 从成人肝脏细胞取得的基因组稳定的双潜能 干 细胞的长期培养 Meritxell Huch,1,9,10,* Helmuth Gehart,1,9 Ruben van Boxtel,1,9 Karien Hamer,1 Francis Blokzijl,1 Monique M.
2、A. Verstegen,2 Ewa Ellis,7 Martien van Wenum,3 Sabine A. Fuchs,4 Joep de Ligt,1 Marc van de Wetering,1,8 Nobuo Sasaki,1 Susanne J. Boers,4 Hans Kemperman,5 Jeroen de Jonge,2 Jan N.M. Ijzermans,2 Edward E.S. Nieuwenhuis,4 Ruurdtje Hoekstra,3 Stephen Strom,6 Robert R.G. Vries,1,8 Luc J.W. van der Laan
3、,2 Edwin Cuppen,1 and Hans Clevers1,* 1Hubrecht Institute-KNAW, University Medical Centre Utrecht, CancerGenomics.nl, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands 2Department of Surgery, Erasmus MC-University Medical Center, Postbus 2040, 3000 CA Rotterdam, the Netherlands 3Surgical Laboratory, T
4、ytgat Institute for Liver and Intestinal Research, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam,the Netherlands 4Division of Pediatric Gastroenterology, Wilhelmina Childrens Hospital, University Medical Center Utrecht, Lundlaan 6, 3584 EA Utrecht, the Netherlands 5Department of Clinica
5、l Chemistry and Haematology, University Medical Center Utrecht, Lundlaan 6, 3584 EA Utrecht, the Netherlands 6Division of Pathology, Department of Laboratory Medicine, Karolinska Institute, Alfred Nobels Alle 8, F 56 141-86 Stockholm, Sweden 7Unit for Transplantation Surgery, Department of CLINTEC,
6、Karolinska Institute, Karolinska University Hospital Huddinge, Ha lsova gen, Flemingsberg, SE-141 86 Stockholm, Sweden 8Hubrecht Organoid Technology (HUB), Uppsalalaan 8, 3584CT, Utrecht, the Netherlands 9Co-first author 10Present address: Wellcome Trust/Cancer Research UK Gurdon Institute, Wellcome Trust/MRC Stem Cell Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Tennis Court Road, CB2 1QN Cambridge, UK *Correspondence: m.huchgurdon.cam.a
